CMap Candidate Details
Structure:
| CMap ID: | C01836 |
| Pert ID: | BRD-A75144621 |
| Compound Name: | digoxin |
| Targets: | ATP1A1 |
| MoA: | ATPase inhibitor |
| SMILES: | C[C@H]1O[C@H](C[C@H](O)[C@@H]1O)O[C@H]1[C@@H](O)C[C@H](O[C@H]2[C@@H](O)C[C@H](O[C@H]3CC[C@@]4(C)[C@H](CC[C@@H]5[C@@H]4C[C@@H](O)[C@]4(C)C(CC[C@]54O)C4=CC(=O)OC4)C3)O[C@@H]2C)O[C@@H]1C |
| InchiKey: | LTMHDMANZUZIPE-YUICGFAKSA-N |
| Compound Aliases: | -- |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 49776 | BRD-A75144621 | A375 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.43 | -1.45 | 15.35 |
| 49956 | BRD-A75144621 | A549 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.47 | -1.57 | 15.65 |
| 50119 | BRD-A75144621 | HA1E | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.49 | -1.63 | 15.65 |
| 50309 | BRD-A75144621 | HCC515 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 50470 | BRD-A75144621 | HT29 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 50720 | BRD-A75144621 | MCF??7.00 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 50811 | BRD-A75144621 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.55 | -1.84 | 15.65 |
| 51105 | BRD-A75144621 | VCAP | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |