CMap Candidate Details

Structure:
CMap ID: C18415
Pert ID: BRD-K50163129
Compound Name: acrivastine
Targets: HRH1
MoA: Histamine receptor antagonist
SMILES: Cc1ccc(cc1)C(=C/CN1CCCC1)c1cccc(C=CC(O)=O)n1
InchiKey: PWACSDKDOHSSQD-IUTFFREVSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
124566 BRD-K50163129 A375 0.37 uM 24 h 0.23 0.95 0.07 0.0 0.0 0.0
124590 BRD-K50163129 A549 1.11 uM 24 h 0.0 0.0 0.0 0.23 0.81 0.09
124645 BRD-K50163129 HELA 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124750 BRD-K50163129 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.26 -0.89 0.27
124772 BRD-K50163129 MDAMB231 0.37 uM 24 h -0.21 -0.89 0.03 0.0 0.0 0.0
124820 BRD-K50163129 PC3 10 uM 24 h 0.0 0.0 0.0 0.22 0.79 0.07
124863 BRD-K50163129 THP1 0.125 uM 24 h -0.24 -1.01 0.17 -0.24 -0.79 0.11
124903 BRD-K50163129 YAPC 10 uM 24 h 0.0 0.0 0.0 -0.2 -0.68 0.02
132708 BRD-K50163129 HA1E 0.74 uM 24 h 0.0 0.0 0.0 0.22 0.8 0.08
132733 BRD-K50163129 HEK293 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132801 BRD-K50163129 HT29 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132820 BRD-K50163129 JURKAT 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132850 BRD-K50163129 MCF10A 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).