CMap Candidate Details

Structure:
CMap ID: C18434
Pert ID: BRD-K50214219
Compound Name: CS-1657
Targets: PARP1
MoA: PARP inhibitor
SMILES: Nc1ccc2C(=O)NC(=O)c3cccc1c32
InchiKey: SSMIFVHARFVINF-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6766 BRD-K50214219 A375 10 uM 24 h -0.23 -0.97 0.1 0.0 0.0 0.0
7005 BRD-K50214219 A549 10 uM 24 h 0.0 0.0 0.0 0.32 1.14 0.87
7334 BRD-K50214219 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.25 -0.84 0.17
7674 BRD-K50214219 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.27 -0.9 0.29
7880 BRD-K50214219 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
8261 BRD-K50214219 MCF??7.00 10 uM 6 h 0.21 0.86 0.01 -0.21 -0.69 0.02
8380 BRD-K50214219 PC3 10 uM 24 h 0.0 0.0 0.0 0.21 0.75 0.04
8825 BRD-K50214219 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
99613 BRD-K50214219 U2OS 25 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).