CMap Candidate Details

Structure:
CMap ID: C01845
Pert ID: BRD-A75455249
Compound Name: kavain
Targets: MTOR
MoA: Sodium channel blocker; Calcium channel modulator
SMILES: COC1=CC(=O)OC(C1)/C=C/c2ccccc2
InchiKey: XEAQIWGXBXCYFX-BQYQJAHWSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4029 BRD-A75455249 HA1E 10 uM 24 h -0.26 -1.08 0.3 -0.24 -0.8 0.12
4321 BRD-A75455249 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4627 BRD-A75455249 PC3 10 uM 24 h 0.29 1.22 0.48 0.0 0.0 0.0
4864 BRD-A75455249 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37102 BRD-A75455249 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37253 BRD-A75455249 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37550 BRD-A75455249 ASC 10 uM 24 h 0.0 0.0 0.0 -0.34 -1.13 0.99
37852 BRD-A75455249 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38039 BRD-A75455249 HT29 10 uM 6 h 0.24 1.01 0.12 0.26 0.93 0.27
38243 BRD-A75455249 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38663 BRD-A75455249 PHH 10 uM 24 h -0.29 -1.2 0.55 0.0 0.0 0.0
98200 BRD-A75455249 NPC 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
98574 BRD-A75455249 NEU 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
99267 BRD-A75455249 U2OS 20 uM 6 h 0.0 0.0 0.0 0.21 0.76 0.05
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).