CMap Candidate Details

Structure:
CMap ID: C18465
Pert ID: BRD-K50311478
Compound Name: BRD-K50311478
Targets: --
MoA: --
SMILES: Cc1ccc(cc1)S(=O)(=O)N[C@H](Cc2ccccc2)C(=O)CCl
InchiKey: MQUQNUAYKLCRME-MRXNPFEDSA-N
Compound Aliases: tosyl-phenylalanyl-chloromethyl-ketone

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5213 BRD-K50311478 A375 10 uM 6 h -0.23 -0.96 0.1 0.31 1.09 0.67
5339 BRD-K50311478 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.2 -0.66 0.01
5785 BRD-K50311478 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
5925 BRD-K50311478 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6284 BRD-K50311478 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6563 BRD-K50311478 VCAP 10 uM 6 h 0.0 0.0 0.0 0.29 1.02 0.48
39457 BRD-K50311478 A549 10 uM 6 h -0.22 -0.91 0.05 -0.27 -0.92 0.32
39710 BRD-K50311478 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
40286 BRD-K50311478 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40623 BRD-K50311478 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.3 1.07 0.64
40824 BRD-K50311478 NEU 10 uM 24 h 0.16 0.68 0.0 -0.35 -1.17 1.14
41131 BRD-K50311478 NPC 10 uM 24 h -0.16 -0.65 0.0 0.0 0.0 0.0
41466 BRD-K50311478 SKB 10 uM 24 h 0.0 0.0 0.0 0.32 1.13 0.85
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).