CMap Candidate Details

Structure:
CMap ID: C18511
Pert ID: BRD-K50464341
Compound Name: berbamine
Targets: CALM1
MoA: Calmodulin antagonist
SMILES: COc1cc2CCN(C)[C@@H]3Cc4ccc(OC(=O)c5ccc(cc5)[N+](=O)[O-])c(Oc6ccc(C[C@@H]7N(C)CCc8cc(OC)c(Oc(c1OC)c32)cc78)cc6)c4
InchiKey: PUAVTDKYTXNVBU-OIDHKYIRSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6768 BRD-K50464341 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
7169 BRD-K50464341 A549 10 uM 6 h -0.21 -0.87 0.02 0.36 1.28 1.37
7335 BRD-K50464341 HA1E 10 uM 24 h 0.34 1.42 1.09 0.39 1.39 2.17
7675 BRD-K50464341 HCC515 10 uM 6 h 0.28 1.16 0.35 0.0 0.0 0.0
7881 BRD-K50464341 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
8249 BRD-K50464341 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8381 BRD-K50464341 PC3 10 uM 24 h 0.21 0.86 0.01 0.0 0.0 0.0
8693 BRD-K50464341 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).