CMap Candidate Details

Structure:
CMap ID: C18519
Pert ID: BRD-K50495309
Compound Name: BRD-K50495309
Targets: --
MoA: --
SMILES: COc1cc2ncnc(Nc3ccc(Oc4ccccc4)cc3)c2cc1OC
InchiKey: DMWVGXGXHPOEPT-UHFFFAOYSA-N
Compound Aliases: SRC-kinase-inhibitor-I

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6769 BRD-K50495309 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
7170 BRD-K50495309 A549 10 uM 6 h -0.22 -0.93 0.07 -0.37 -1.24 1.3
7336 BRD-K50495309 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
7676 BRD-K50495309 HCC515 10 uM 6 h -0.2 -0.82 0.0 0.0 0.0 0.0
7882 BRD-K50495309 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
8102 BRD-K50495309 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.24 -0.82 0.15
8382 BRD-K50495309 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
8694 BRD-K50495309 VCAP 10 uM 24 h -0.23 -0.95 0.09 -0.27 -0.9 0.29
87281 BRD-K50495309 BJAB 10 uM 24 h 0.23 0.97 0.08 0.0 0.0 0.0
87333 BRD-K50495309 HBL1 2.5 uM 24 h 0.25 1.04 0.14 0.32 1.13 0.84
87381 BRD-K50495309 K562 10 uM 24 h -0.22 -0.91 0.06 0.38 1.34 1.72
87430 BRD-K50495309 KMS34 10 uM 24 h -0.18 -0.73 0.0 0.0 0.0 0.0
87511 BRD-K50495309 MINO 10 uM 6 h -0.28 -1.15 0.43 0.0 0.0 0.0
87532 BRD-K50495309 NALM6 0.125 uM 24 h -0.24 -1.01 0.16 -0.26 -0.86 0.21
87582 BRD-K50495309 OCILY10 10 uM 24 h 0.0 0.0 0.0 0.29 1.02 0.49
87634 BRD-K50495309 OCILY19 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
87683 BRD-K50495309 OCILY3 10 uM 24 h 0.0 0.0 0.0 0.34 1.21 1.13
87734 BRD-K50495309 SKMEL5 10 uM 24 h 0.0 0.0 0.0 0.4 1.42 2.2
87810 BRD-K50495309 THP1 10 uM 6 h 0.0 0.0 0.0 -0.37 -1.23 1.28
87825 BRD-K50495309 TMD8 10 uM 24 h 0.0 0.0 0.0 -0.24 -0.81 0.13
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).