CMap Candidate Details

Structure:
CMap ID: C18536
Pert ID: BRD-K50564936
Compound Name: E-2012
Targets: --
MoA: --
SMILES: COc1cc(ccc1-n1cnc(C)c1)C=C1/CCCN([C@@H](C)c2ccc(F)cc2)C1=O
InchiKey: PUOAETJYKQITMO-LANLRWRYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
125248 BRD-K50564936 A375 10 uM 24 h -0.23 -0.95 0.09 0.0 0.0 0.0
125266 BRD-K50564936 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125337 BRD-K50564936 HEK293 10 uM 24 h -0.22 -0.93 0.07 -0.22 -0.75 0.06
125359 BRD-K50564936 HELA 10 uM 24 h 0.0 0.0 0.0 0.29 1.02 0.48
125384 BRD-K50564936 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125424 BRD-K50564936 MCF10A 10 uM 24 h 0.0 0.0 0.0 -0.45 -1.51 15.35
125464 BRD-K50564936 MCF??7.00 10 uM 24 h -0.33 -1.37 1.08 -0.3 -1.01 0.56
125505 BRD-K50564936 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125532 BRD-K50564936 THP1 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133403 BRD-K50564936 HA1E 2.22 uM 24 h 0.18 0.76 0.0 0.0 0.0 0.0
133496 BRD-K50564936 JURKAT 0.25 uM 24 h 0.0 0.0 0.0 -0.32 -1.09 0.82
133571 BRD-K50564936 MDAMB231 0.08 uM 24 h 0.0 0.0 0.0 0.31 1.1 0.7
133648 BRD-K50564936 YAPC 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).