CMap Candidate Details

Structure:
CMap ID: C18599
Pert ID: BRD-K50776152
Compound Name: BRD-K50776152
Targets: --
MoA: --
SMILES: Cc1ccc(cc1)n2c(N)c(C#N)c(c(C#N)c2=O)c3ccccc3
InchiKey: DWDWEGGEKMILES-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
8949 BRD-K50776152 A375 40 uM 24 h -0.25 -1.06 0.26 0.0 0.0 0.0
9436 BRD-K50776152 AGS 40 uM 6 h 0.2 0.85 0.0 0.0 0.0 0.0
9739 BRD-K50776152 H1299 40 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10268 BRD-K50776152 HCC515 40 uM 6 h 0.0 0.0 0.0 0.2 0.71 0.02
10529 BRD-K50776152 HCT116 40 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11501 BRD-K50776152 NCIH2073 40 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11775 BRD-K50776152 NCIH508 40 uM 6 h 0.0 0.0 0.0 0.22 0.79 0.07
12063 BRD-K50776152 NCIH596 40 uM 6 h 0.0 0.0 0.0 0.32 1.13 0.8
12328 BRD-K50776152 NOMO1 40 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13286 BRD-K50776152 U937 40 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13630 BRD-K50776152 VCAP 40 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
90584 BRD-K50776152 MCF??7.00 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
115116 BRD-K50776152 U2OS 20 uM 6 h 0.0 0.0 0.0 0.23 0.82 0.1
116702 BRD-K50776152 A549 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
116743 BRD-K50776152 HA1E 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
116833 BRD-K50776152 HEPG2 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
116878 BRD-K50776152 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
116967 BRD-K50776152 PC3 0.37 uM 24 h 0.0 0.0 0.0 -0.29 -0.97 0.46
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).