CMap Candidate Details

Structure:
CMap ID: C18621
Pert ID: BRD-K50841342
Compound Name: PAC-1
Targets: CASP3
MoA: Caspase activator
SMILES: Oc1c(CC=C)cccc1C=NNC(=O)CN2CCN(Cc3ccccc3)CC2
InchiKey: YQNRVGJCPCNMKT-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6889 BRD-K50841342 A375 10 uM 6 h -0.23 -0.94 0.08 0.0 0.0 0.0
7172 BRD-K50841342 A549 10 uM 6 h -0.25 -1.04 0.22 0.0 0.0 0.0
7456 BRD-K50841342 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7678 BRD-K50841342 HCC515 10 uM 6 h 0.22 0.9 0.02 0.23 0.82 0.1
7883 BRD-K50841342 HT29 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.12 0.93
8195 BRD-K50841342 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 -0.18 -0.6 0.0
8517 BRD-K50841342 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8695 BRD-K50841342 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99622 BRD-K50841342 U2OS 10 uM 6 h -0.22 -0.9 0.04 0.3 1.08 0.65
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).