CMap Candidate Details

Structure:
CMap ID: C18627
Pert ID: BRD-K50866992
Compound Name: tropisetron
Targets: HTR3A
MoA: Serotonin receptor antagonist
SMILES: CN1[C@H]2CC[C@@H]1C[C@@H](C2)OC(=O)c3c[nH]c4ccccc34
InchiKey: ZNRGQMMCGHDTEI-ITGUQSILSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
24449 BRD-K50866992 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
24676 BRD-K50866992 A549 10 uM 6 h 0.0 0.0 0.0 -0.32 -1.07 0.75
24784 BRD-K50866992 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
24917 BRD-K50866992 HT29 10 uM 6 h 0.0 0.0 0.0 -0.34 -1.15 1.06
25029 BRD-K50866992 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
25166 BRD-K50866992 PC3 10 uM 24 h -0.23 -0.96 0.09 0.0 0.0 0.0
25383 BRD-K50866992 VCAP 10 uM 24 h -0.3 -1.27 0.74 0.0 0.0 0.0
91259 BRD-K50866992 HUH7 12 uM 72 h 0.21 0.86 0.01 0.0 0.0 0.0
136424 BRD-K50866992 SHSY5Y 3.33 uM 24 h 0.0 0.0 0.0 0.32 1.15 0.88
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).