CMap Candidate Details

Structure:
CMap ID: C18694
Pert ID: BRD-K51087630
Compound Name: tirasemtiv
Targets: --
MoA: --
SMILES: CCC(CC)n1c2nc(cnc2[nH]c1=O)C#C
InchiKey: RSQGZEAXODVTOL-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
124312 BRD-K51087630 HEK293 3.33 uM 24 h -0.18 -0.77 0.0 0.0 0.0 0.0
124336 BRD-K51087630 HELA 0.125 uM 24 h 0.0 0.0 0.0 -0.22 -0.74 0.05
124375 BRD-K51087630 HT29 10 uM 24 h 0.27 1.14 0.31 0.0 0.0 0.0
124397 BRD-K51087630 JURKAT 0.37 uM 24 h -0.23 -0.96 0.1 0.0 0.0 0.0
124459 BRD-K51087630 MCF??7.00 1.11 uM 24 h 0.0 0.0 0.0 -0.28 -0.96 0.43
124475 BRD-K51087630 MDAMB231 10 uM 24 h 0.24 1.01 0.12 -0.28 -0.95 0.41
124506 BRD-K51087630 PC3 10 uM 24 h -0.19 -0.79 0.0 -0.33 -1.13 0.98
124532 BRD-K51087630 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132318 BRD-K51087630 A375 0.03 uM 24 h 0.0 0.0 0.0 -0.28 -0.95 0.4
132347 BRD-K51087630 A549 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132375 BRD-K51087630 HA1E 0.25 uM 24 h 0.23 0.98 0.09 0.0 0.0 0.0
132480 BRD-K51087630 MCF10A 0.01 uM 24 h -0.3 -1.23 0.64 0.19 0.67 0.01
132584 BRD-K51087630 THP1 2.22 uM 24 h 0.0 0.0 0.0 0.27 0.97 0.35
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).