CMap Candidate Details

Structure:
CMap ID: C18753
Pert ID: BRD-K51263939
Compound Name: sarcosine
Targets: SLC6A9
MoA: Glycine transporter inhibitor
SMILES: CNCC(O)=O
InchiKey: FSYKKLYZXJSNPZ-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
124376 BRD-K51263939 HT29 1.11 uM 24 h 0.32 1.33 0.87 0.0 0.0 0.0
124398 BRD-K51263939 JURKAT 0.04 uM 24 h 0.0 0.0 0.0 -0.25 -0.85 0.2
124476 BRD-K51263939 MDAMB231 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124507 BRD-K51263939 PC3 1.11 uM 24 h 0.26 1.09 0.24 0.22 0.79 0.07
124533 BRD-K51263939 YAPC 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132319 BRD-K51263939 A375 0.01 uM 24 h 0.0 0.0 0.0 0.33 1.16 0.9
132348 BRD-K51263939 A549 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132376 BRD-K51263939 HA1E 0.01 uM 24 h 0.0 0.0 0.0 -0.29 -0.97 0.46
132407 BRD-K51263939 HEK293 0.74 uM 24 h 0.0 0.0 0.0 -0.31 -1.05 0.7
132438 BRD-K51263939 HELA 2.22 uM 24 h -0.32 -1.33 0.9 0.0 0.0 0.0
132481 BRD-K51263939 MCF10A 0.08 uM 24 h 0.24 1.0 0.11 0.0 0.0 0.0
132515 BRD-K51263939 MCF??7.00 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132585 BRD-K51263939 THP1 2.22 uM 24 h 0.0 0.0 0.0 0.29 1.03 0.5
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).