CMap Candidate Details

Structure:
CMap ID: C18765
Pert ID: BRD-K51290057
Compound Name: SA-792709
Targets: RARA; RARB
MoA: Retinoid receptor agonist
SMILES: CC(C)(C)c1cc(cc(c1)C(C)(C)C)C(=O)C=Cc2ccc(cc2)C(=O)O
InchiKey: FOUVTBKPJRMLPE-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5340 BRD-K51290057 HA1E 10 uM 24 h 0.0 0.0 0.0 0.24 0.86 0.16
5786 BRD-K51290057 HCC515 10 uM 6 h 0.2 0.85 0.01 0.25 0.9 0.22
5926 BRD-K51290057 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6033 BRD-K51290057 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6105 BRD-K51290057 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 -0.32 -1.07 0.76
6285 BRD-K51290057 PC3 10 uM 6 h -0.25 -1.04 0.21 0.26 0.92 0.25
6415 BRD-K51290057 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44415 BRD-K51290057 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44716 BRD-K51290057 A549 10 uM 6 h -0.18 -0.77 0.0 0.0 0.0 0.0
44983 BRD-K51290057 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46099 BRD-K51290057 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46414 BRD-K51290057 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46738 BRD-K51290057 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).