CMap Candidate Details

Structure:
CMap ID: C18771
Pert ID: BRD-K51318897
Compound Name: fenbendazole
Targets: TUBB
MoA: Tubulin inhibitor
SMILES: COC(=O)Nc1nc2ccc(Sc3ccccc3)cc2[nH]1
InchiKey: HDDSHPAODJUKPD-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2893 BRD-K51318897 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.26 -0.88 0.25
3223 BRD-K51318897 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3824 BRD-K51318897 VCAP 10 uM 24 h -0.22 -0.9 0.04 0.25 0.88 0.18
44416 BRD-K51318897 A375 10 uM 6 h 0.0 0.0 0.0 -0.33 -1.11 0.91
44984 BRD-K51318897 ASC 10 uM 24 h 0.0 0.0 0.0 0.29 1.04 0.54
45278 BRD-K51318897 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45545 BRD-K51318897 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
46100 BRD-K51318897 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46415 BRD-K51318897 PHH 10 uM 24 h 0.29 1.23 0.5 0.0 0.0 0.0
46739 BRD-K51318897 SKB 10 uM 24 h -0.23 -0.98 0.12 0.0 0.0 0.0
51478 BRD-K51318897 PC3 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.11 0.9
91315 BRD-K51318897 HUH7 12 uM 72 h -0.25 -1.04 0.21 -0.21 -0.7 0.03
95530 BRD-K51318897 A549 10 uM 6 h -0.27 -1.13 0.4 -0.45 -1.51 15.35
95554 BRD-K51318897 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
95696 BRD-K51318897 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).