CMap Candidate Details

Structure:
CMap ID: C18777
Pert ID: BRD-K51324732
Compound Name: meglitinide
Targets: --
MoA: --
SMILES: COc1ccc(Cl)cc1C(=O)NCCc1ccc(cc1)C(O)=O
InchiKey: SWLAMJPTOQZTAE-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
124337 BRD-K51324732 HELA 0.125 uM 24 h 0.38 1.58 1.51 0.0 0.0 0.0
124399 BRD-K51324732 JURKAT 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124444 BRD-K51324732 MCF10A 0.04 uM 24 h 0.0 0.0 0.0 -0.25 -0.83 0.16
124508 BRD-K51324732 PC3 1.11 uM 24 h -0.27 -1.13 0.4 0.22 0.76 0.05
132320 BRD-K51324732 A375 0.03 uM 24 h -0.24 -1.01 0.16 -0.24 -0.81 0.13
132349 BRD-K51324732 A549 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132377 BRD-K51324732 HA1E 0.25 uM 24 h 0.0 0.0 0.0 -0.3 -1.0 0.55
132408 BRD-K51324732 HEK293 0.01 uM 24 h -0.22 -0.92 0.06 0.29 1.04 0.56
132454 BRD-K51324732 HT29 0.01 uM 24 h 0.0 0.0 0.0 0.34 1.19 1.05
132516 BRD-K51324732 MCF??7.00 0.01 uM 24 h -0.21 -0.85 0.01 -0.28 -0.93 0.34
132543 BRD-K51324732 MDAMB231 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132586 BRD-K51324732 THP1 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132635 BRD-K51324732 YAPC 0.08 uM 24 h 0.0 0.0 0.0 -0.25 -0.84 0.18
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).