CMap Candidate Details

Structure:
CMap ID: C01881
Pert ID: BRD-A76941896
Compound Name: doxorubicin
Targets: TOP2A
MoA: Topoisomerase inhibitor
SMILES: COc1cccc2C(=O)c3c(O)c4CC(O)(CC(OC5CC(N)C(O)C(C)O5)c4c(O)c3C(=O)c12)C(=O)CO
InchiKey: AOJJSUZBOXZQNB-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6854 BRD-A76941896 A375 10 uM 6 h 0.0 0.0 0.0 0.36 1.27 1.34
7114 BRD-A76941896 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7413 BRD-A76941896 HA1E 10 uM 6 h 0.0 0.0 0.0 0.41 1.46 2.23
7590 BRD-A76941896 HCC515 10 uM 6 h 0.0 0.0 0.0 0.41 1.44 2.21
7970 BRD-A76941896 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8178 BRD-A76941896 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8471 BRD-A76941896 PC3 10 uM 6 h 0.0 0.0 0.0 0.33 1.18 0.98
8779 BRD-A76941896 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).