CMap Candidate Details

Structure:
CMap ID: C18850
Pert ID: BRD-K51541829
Compound Name: Ro-25-6981
Targets: GRIN2B
MoA: Monamine transporter modulator; Ionotropic glutamate receptor antagonist
SMILES: C[C@@H](CN1CCC(Cc2ccccc2)CC1)[C@@H](O)c1ccc(O)cc1
InchiKey: WVZSEUPGUDIELE-HTAPYJJXSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6775 BRD-K51541829 A375 10 uM 24 h 0.0 0.0 0.0 0.25 0.9 0.22
7176 BRD-K51541829 A549 10 uM 6 h -0.31 -1.3 0.8 0.0 0.0 0.0
7461 BRD-K51541829 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7682 BRD-K51541829 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.36 -1.22 1.24
8011 BRD-K51541829 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8106 BRD-K51541829 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
8387 BRD-K51541829 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
8700 BRD-K51541829 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).