CMap Candidate Details

Structure:
CMap ID: C18892
Pert ID: BRD-K51671335
Compound Name: levosulpiride
Targets: DRD2; DRD3
MoA: Dopamine receptor antagonist
SMILES: CCN1CCC[C@H]1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O
InchiKey: BGRJTUBHPOOWDU-NSHDSACASA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1158 BRD-K51671335 MCF??7.00 10 uM 24 h -0.22 -0.91 0.05 -0.27 -0.91 0.31
1184 BRD-K51671335 PC3 10 uM 24 h 0.0 0.0 0.0 0.38 1.36 1.72
1219 BRD-K51671335 A549 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
1378 BRD-K51671335 U2OS 1.11 uM 6 h 0.19 0.81 0.0 0.3 1.07 0.63
24450 BRD-K51671335 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
24918 BRD-K51671335 HT29 10 uM 6 h 0.0 0.0 0.0 -0.31 -1.04 0.67
25385 BRD-K51671335 VCAP 10 uM 24 h 0.0 0.0 0.0 0.29 1.03 0.52
90974 BRD-K51671335 HUH7 10 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).