CMap Candidate Details

Structure:
CMap ID: C18934
Pert ID: BRD-K51791390
Compound Name: BRD-K51791390
Targets: --
MoA: --
SMILES: C[C@@H](CO)N1C[C@H](C)[C@@H](CN(C)Cc2ccc(cc2)C(=O)Nc3ccccc3N)Oc4c(NC(=O)c5ccc(cc5)c6nccs6)cccc4C1=O
InchiKey: UIWHTZIAIXNFGN-SFXKCFQESA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
25771 BRD-K51791390 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
26130 BRD-K51791390 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
26383 BRD-K51791390 ASC 10 uM 24 h 0.0 0.0 0.0 0.26 0.92 0.26
26713 BRD-K51791390 HA1E 10 uM 6 h 0.0 0.0 0.0 0.25 0.88 0.19
27015 BRD-K51791390 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
27325 BRD-K51791390 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
27565 BRD-K51791390 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
27957 BRD-K51791390 NEU 10 uM 24 h 0.28 1.17 0.37 0.0 0.0 0.0
28270 BRD-K51791390 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
28656 BRD-K51791390 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
28901 BRD-K51791390 PHH 10 uM 24 h 0.0 0.0 0.0 -0.25 -0.84 0.18
29233 BRD-K51791390 SKB 10 uM 24 h 0.2 0.83 0.0 0.0 0.0 0.0
29497 BRD-K51791390 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).