CMap Candidate Details

Structure:
CMap ID: C18942
Pert ID: BRD-K51816706
Compound Name: oxindole-I
Targets: KDR
MoA: VEGFR inhibitor
SMILES: O=C/1Nc2ccccc2C1=Cc3ccc[nH]3
InchiKey: SEZFNTZQMWJIAI-FLIBITNWSA-N
Compound Aliases: oxindole-i

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1587 BRD-K51816706 HA1E 10 uM 24 h -0.26 -1.08 0.3 0.0 0.0 0.0
1921 BRD-K51816706 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2399 BRD-K51816706 PC3 10 uM 6 h 0.0 0.0 0.0 -0.32 -1.09 0.82
2633 BRD-K51816706 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41782 BRD-K51816706 A375 10 uM 6 h 0.0 0.0 0.0 -0.24 -0.82 0.15
41944 BRD-K51816706 A549 10 uM 24 h 0.26 1.07 0.19 0.34 1.19 1.03
42382 BRD-K51816706 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42703 BRD-K51816706 HEPG2 10 uM 6 h -0.22 -0.9 0.04 0.0 0.0 0.0
43005 BRD-K51816706 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43199 BRD-K51816706 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.44 -1.48 15.35
43570 BRD-K51816706 NPC 10 uM 24 h -0.24 -0.98 0.13 -0.42 -1.4 2.02
43870 BRD-K51816706 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).