CMap Candidate Details

Structure:
CMap ID: C18979
Pert ID: BRD-K51941867
Compound Name: LM-1685
Targets: PTGS2
MoA: Cyclooxygenase inhibitor
SMILES: COC(=O)c1cc2cc(ccc2n1Cc1ccc(Cl)cc1)S(C)(=O)=O
InchiKey: UBZBOEWMQPWUKB-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
25621 BRD-K51941867 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
26131 BRD-K51941867 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
26384 BRD-K51941867 ASC 10 uM 24 h 0.0 0.0 0.0 -0.42 -1.42 2.17
26714 BRD-K51941867 HA1E 10 uM 6 h 0.0 0.0 0.0 0.24 0.85 0.14
27016 BRD-K51941867 HCC515 10 uM 6 h -0.25 -1.06 0.26 -0.32 -1.07 0.76
27326 BRD-K51941867 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
27566 BRD-K51941867 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
27958 BRD-K51941867 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
28271 BRD-K51941867 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
28491 BRD-K51941867 PC3 10 uM 24 h 0.0 0.0 0.0 -0.3 -1.0 0.53
28902 BRD-K51941867 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
29498 BRD-K51941867 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).