CMap Candidate Details

Structure:
CMap ID: C19022
Pert ID: BRD-K52075715
Compound Name: oxibendazole
Targets: TUBB
MoA: Tubulin inhibitor
SMILES: CCCOc1ccc2nc(NC(=O)OC)[nH]c2c1
InchiKey: RAOCRURYZCVHMG-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5462 BRD-K52075715 HA1E 10 uM 6 h 0.0 0.0 0.0 0.3 1.07 0.62
5645 BRD-K52075715 HCC515 10 uM 24 h -0.3 -1.27 0.74 0.0 0.0 0.0
5927 BRD-K52075715 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6034 BRD-K52075715 HT29 10 uM 6 h 0.0 0.0 0.0 0.23 0.8 0.08
6337 BRD-K52075715 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37170 BRD-K52075715 A375 10 uM 6 h -0.22 -0.9 0.04 -0.27 -0.91 0.31
37295 BRD-K52075715 A549 10 uM 24 h -0.24 -0.99 0.14 0.0 0.0 0.0
37686 BRD-K52075715 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38509 BRD-K52075715 NPC 10 uM 24 h 0.22 0.93 0.05 -0.45 -1.5 15.35
38970 BRD-K52075715 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
51615 BRD-K52075715 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.23 -0.78 0.09
51831 BRD-K52075715 PC3 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.11 0.9
91303 BRD-K52075715 HUH7 12.5 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).