CMap Candidate Details

Structure:
CMap ID: C01905
Pert ID: BRD-A77824596
Compound Name: fluocinolone-acetonide
Targets: NR3C1
MoA: Corticosteroid agonist; Glucocorticoid receptor agonist
SMILES: CC1(C)O[C@@H]2CC3C4C[C@H](F)C5=CC(=O)C=C[C@]5(C)[C@@]4(F)[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)CO
InchiKey: FEBLZLNTKCEFIT-AHVBUMMWSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6692 BRD-A77824596 A375 10 uM 24 h 0.23 0.97 0.08 -0.23 -0.76 0.07
6956 BRD-A77824596 A549 10 uM 24 h 0.0 0.0 0.0 -0.35 -1.17 1.14
7265 BRD-A77824596 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.27 -0.9 0.29
7807 BRD-A77824596 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
8063 BRD-A77824596 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.21 -0.7 0.03
8473 BRD-A77824596 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8621 BRD-A77824596 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.4 -1.35 2.02
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).