CMap Candidate Details

Structure:
CMap ID: C19058
Pert ID: BRD-K52172416
Compound Name: anastrozole
Targets: CYP19A1
MoA: Aromatase inhibitor
SMILES: CC(C)(C#N)c1cc(Cn2cncn2)cc(c1)C(C)(C)C#N
InchiKey: YBBLVLTVTVSKRW-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
23080 BRD-K52172416 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.39 -1.32 1.71
24169 BRD-K52172416 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
91146 BRD-K52172416 HUH7 12 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
118417 BRD-K52172416 A549 0.04 uM 24 h 0.28 1.18 0.39 0.0 0.0 0.0
118487 BRD-K52172416 HCC515 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121563 BRD-K52172416 A375 10 uM 24 h 0.31 1.31 0.76 0.0 0.0 0.0
121601 BRD-K52172416 HA1E 10 uM 24 h -0.27 -1.12 0.39 0.0 0.0 0.0
121639 BRD-K52172416 HELA 10 uM 24 h 0.0 0.0 0.0 -0.36 -1.2 1.21
121682 BRD-K52172416 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129633 BRD-K52172416 HT29 0.25 uM 24 h -0.22 -0.93 0.07 0.0 0.0 0.0
129692 BRD-K52172416 PC3 0.25 uM 24 h -0.33 -1.38 1.09 -0.25 -0.84 0.18
129725 BRD-K52172416 YAPC 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).