CMap Candidate Details

Structure:
CMap ID: C19087
Pert ID: BRD-K52233191
Compound Name: R-547
Targets: --
MoA: --
SMILES: COc1ccc(F)c(F)c1C(=O)c1cnc(NC2CCN(CC2)S(C)(=O)=O)nc1N
InchiKey: JRNJNYBQQYBCLE-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1300 BRD-K52233191 MCF??7.00 1.11 uM 6 h 0.0 0.0 0.0 0.3 1.05 0.57
1314 BRD-K52233191 U2OS 1.11 uM 24 h -0.26 -1.1 0.34 0.0 0.0 0.0
90840 BRD-K52233191 MCF10A 1.11 uM 24 h -0.27 -1.14 0.42 0.26 0.93 0.27
97266 BRD-K52233191 HAP1 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
97341 BRD-K52233191 A375 0.66 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124380 BRD-K52233191 HT29 0.37 uM 24 h 0.16 0.68 0.0 -0.31 -1.05 0.7
124406 BRD-K52233191 JURKAT 3.33 uM 24 h 0.0 0.0 0.0 -0.24 -0.81 0.14
124483 BRD-K52233191 MDAMB231 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124511 BRD-K52233191 PC3 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124538 BRD-K52233191 YAPC 0.37 uM 24 h 0.0 0.0 0.0 0.39 1.37 1.97
132352 BRD-K52233191 A549 0.25 uM 24 h -0.24 -0.98 0.12 0.0 0.0 0.0
132382 BRD-K52233191 HA1E 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132414 BRD-K52233191 HEK293 2.22 uM 24 h -0.22 -0.93 0.07 -0.38 -1.28 1.45
132439 BRD-K52233191 HELA 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132594 BRD-K52233191 THP1 0.74 uM 24 h -0.27 -1.14 0.42 -0.24 -0.8 0.12
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).