CMap Candidate Details

Structure:
CMap ID: C19128
Pert ID: BRD-K52394958
Compound Name: GR-159897
Targets: TAC1; TACR2
MoA: Tachykinin antagonist
SMILES: COC1(C[S@@](=O)c2ccccc2)CCN(CCc2c[nH]c3ccc(F)cc23)CC1
InchiKey: BANYJBHWTOJQDU-GDLZYMKVSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2896 BRD-K52394958 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3226 BRD-K52394958 HCC515 10 uM 24 h 0.0 0.0 0.0 0.26 0.91 0.23
3629 BRD-K52394958 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3827 BRD-K52394958 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41784 BRD-K52394958 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
41945 BRD-K52394958 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42384 BRD-K52394958 ASC 10 uM 24 h -0.26 -1.07 0.28 0.27 0.97 0.34
42705 BRD-K52394958 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43007 BRD-K52394958 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43200 BRD-K52394958 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43572 BRD-K52394958 NPC 10 uM 24 h 0.0 0.0 0.0 -0.39 -1.32 1.71
43872 BRD-K52394958 PHH 10 uM 24 h 0.16 0.68 0.0 0.0 0.0 0.0
44131 BRD-K52394958 SKB 10 uM 24 h -0.19 -0.78 0.0 0.3 1.06 0.59
99635 BRD-K52394958 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).