CMap Candidate Details

Structure:
CMap ID: C19129
Pert ID: BRD-K52397688
Compound Name: amperozide
Targets: DRD2; HTR2A
MoA: Dopamine receptor antagonist
SMILES: CCNC(=O)N1CCN(CCCC(c2ccc(F)cc2)c2ccc(F)cc2)CC1
InchiKey: NNAIYOXJNVGUOM-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5464 BRD-K52397688 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
5647 BRD-K52397688 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
6106 BRD-K52397688 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6200 BRD-K52397688 PC3 10 uM 24 h -0.26 -1.06 0.26 -0.21 -0.71 0.03
6566 BRD-K52397688 VCAP 10 uM 6 h 0.0 0.0 0.0 0.34 1.19 1.03
37171 BRD-K52397688 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37297 BRD-K52397688 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37688 BRD-K52397688 ASC 10 uM 24 h 0.29 1.23 0.49 0.29 1.03 0.51
37918 BRD-K52397688 HEPG2 10 uM 6 h -0.26 -1.09 0.33 -0.29 -0.97 0.46
38095 BRD-K52397688 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38511 BRD-K52397688 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38743 BRD-K52397688 PHH 10 uM 24 h 0.31 1.3 0.72 0.0 0.0 0.0
99636 BRD-K52397688 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).