CMap Candidate Details

Structure:
CMap ID: C19152
Pert ID: BRD-K52459643
Compound Name: alprostadil
Targets: PTGER1; PTGER2
MoA: Prostanoid receptor agonist
SMILES: CCCCC[C@H](O)C=C[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(O)=O
InchiKey: GMVPRGQOIOIIMI-DWKJAMRDSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
3037 BRD-K52459643 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3377 BRD-K52459643 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3522 BRD-K52459643 PC3 10 uM 24 h 0.17 0.71 0.0 -0.35 -1.17 1.14
3828 BRD-K52459643 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41785 BRD-K52459643 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
41946 BRD-K52459643 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42385 BRD-K52459643 ASC 10 uM 24 h 0.0 0.0 0.0 -0.25 -0.85 0.19
42706 BRD-K52459643 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.39 -1.33 1.71
43008 BRD-K52459643 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43326 BRD-K52459643 MCF??7.00 10 uM 6 h -0.31 -1.29 0.79 0.0 0.0 0.0
43873 BRD-K52459643 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44132 BRD-K52459643 SKB 10 uM 24 h 0.0 0.0 0.0 -0.37 -1.24 1.3
91410 BRD-K52459643 HUH7 10 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
99637 BRD-K52459643 U2OS 10 uM 6 h 0.24 1.02 0.12 -0.29 -0.98 0.49
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).