CMap Candidate Details

Structure:
CMap ID: C19167
Pert ID: BRD-K52522949
Compound Name: NCH-51
Targets: HDAC6; HDAC5; HDAC1; HDAC2; HDAC7; HDAC8; HDAC11; HDAC10; HDAC3; HDAC9; HDAC4
MoA: HDAC inhibitor
SMILES: CC(C)C(=O)SCCCCCCC(=O)Nc1nc(cs1)-c1ccccc1
InchiKey: MDYDGUOQFUQOGE-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
49856 BRD-K52522949 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50199 BRD-K52522949 HA1E 10 uM 6 h -0.21 -0.88 0.03 0.26 0.91 0.23
50373 BRD-K52522949 HCC515 10 uM 6 h 0.0 0.0 0.0 0.27 0.97 0.35
50549 BRD-K52522949 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50673 BRD-K52522949 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
50935 BRD-K52522949 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
51039 BRD-K52522949 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
96154 BRD-K52522949 A549 10 uM 24 h 0.0 0.0 0.0 -0.34 -1.14 1.03
99054 BRD-K52522949 NEU 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
99157 BRD-K52522949 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).