CMap Candidate Details

Structure:
CMap ID: C01918
Pert ID: BRD-A78322124
Compound Name: dobutamine
Targets: ADRB1; ADRB2
MoA: Adrenergic receptor agonist
SMILES: CC(CCc1ccc(O)cc1)NCCc1ccc(O)c(O)c1
InchiKey: JRWZLRBJNMZMFE-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2973 BRD-A78322124 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3118 BRD-A78322124 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3702 BRD-A78322124 VCAP 10 uM 24 h -0.18 -0.75 0.0 -0.28 -0.93 0.34
44260 BRD-A78322124 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44651 BRD-A78322124 A549 10 uM 6 h -0.35 -1.46 1.43 0.0 0.0 0.0
44786 BRD-A78322124 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
45106 BRD-A78322124 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45377 BRD-A78322124 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45906 BRD-A78322124 NPC 10 uM 24 h -0.23 -0.94 0.08 -0.23 -0.78 0.09
46222 BRD-A78322124 PHH 10 uM 24 h 0.25 1.03 0.14 -0.27 -0.92 0.31
46537 BRD-A78322124 SKB 10 uM 24 h 0.0 0.0 0.0 -0.29 -0.97 0.45
51312 BRD-A78322124 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.35 1.25 1.29
51411 BRD-A78322124 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
91085 BRD-A78322124 HUH7 12 uM 72 h 0.0 0.0 0.0 -0.25 -0.83 0.17
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).