CMap Candidate Details

Structure:
CMap ID: C19191
Pert ID: BRD-K52620403
Compound Name: STO-609
Targets: CAMKK2; CAMKK1
MoA: Calmodulin antagonist
SMILES: OC(=O)c1ccc2c3nc4ccccc4n3c(=O)c5cccc1c52
InchiKey: MYKOWOGZBMOVBJ-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2897 BRD-K52620403 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.34 -1.14 1.01
3378 BRD-K52620403 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3967 BRD-K52620403 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
41947 BRD-K52620403 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42386 BRD-K52620403 ASC 10 uM 24 h 0.29 1.19 0.42 0.0 0.0 0.0
42707 BRD-K52620403 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43009 BRD-K52620403 HT29 10 uM 6 h 0.0 0.0 0.0 -0.27 -0.91 0.3
43327 BRD-K52620403 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 -0.25 -0.83 0.17
43573 BRD-K52620403 NPC 10 uM 24 h 0.0 0.0 0.0 -0.24 -0.82 0.14
43874 BRD-K52620403 PHH 10 uM 24 h 0.24 1.02 0.12 0.28 0.98 0.37
97162 BRD-K52620403 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
97227 BRD-K52620403 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99280 BRD-K52620403 U2OS 12.5 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).