CMap Candidate Details

Structure:
CMap ID: C19195
Pert ID: BRD-K52640952
Compound Name: BRD-K52640952
Targets: PLA2G1B
MoA: Topoisomerase inhibitor
SMILES: COc1cc(O)c2C(=O)C[C@@H](Oc2c1)c3ccccc3
InchiKey: ORJDDOBAOGKRJV-CQSZACIVSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
29873 BRD-K52640952 A375 10 uM 6 h -0.18 -0.75 0.0 0.24 0.85 0.15
30073 BRD-K52640952 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
30467 BRD-K52640952 ASC 10 uM 24 h 0.0 0.0 0.0 -0.34 -1.14 1.05
30769 BRD-K52640952 HA1E 10 uM 6 h 0.0 0.0 0.0 0.25 0.88 0.19
31063 BRD-K52640952 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
31369 BRD-K52640952 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.22 0.79 0.08
31730 BRD-K52640952 HT29 10 uM 6 h 0.27 1.13 0.28 -0.23 -0.78 0.09
32039 BRD-K52640952 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 -0.23 -0.77 0.09
32448 BRD-K52640952 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
32789 BRD-K52640952 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
33475 BRD-K52640952 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).