CMap Candidate Details

Structure:
CMap ID: C19223
Pert ID: BRD-K52721684
Compound Name: PCO-400
Targets: KCNJ8
MoA: Potassium channel activator
SMILES: CC1(C)Oc2ccc(cc2[C@@H](OC2=CC(=O)CC2)[C@@H]1O)C#N
InchiKey: WJBHHTPFTVKZCV-CVEARBPZSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2898 BRD-K52721684 HA1E 10 uM 24 h 0.19 0.81 0.0 0.25 0.89 0.2
3227 BRD-K52721684 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3630 BRD-K52721684 PC3 10 uM 6 h 0.0 0.0 0.0 0.22 0.79 0.07
3968 BRD-K52721684 VCAP 10 uM 6 h 0.0 0.0 0.0 -0.33 -1.1 0.86
41786 BRD-K52721684 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42103 BRD-K52721684 A549 10 uM 6 h 0.0 0.0 0.0 -0.23 -0.79 0.11
42387 BRD-K52721684 ASC 10 uM 24 h 0.0 0.0 0.0 0.25 0.88 0.19
43010 BRD-K52721684 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43201 BRD-K52721684 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.27 -0.9 0.29
43574 BRD-K52721684 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43875 BRD-K52721684 PHH 10 uM 24 h 0.0 0.0 0.0 0.26 0.94 0.28
99640 BRD-K52721684 U2OS 15 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).