CMap Candidate Details

Structure:
CMap ID: C01924
Pert ID: BRD-A78723049
Compound Name: cefotetan
Targets: --
MoA: --
SMILES: CO[C@]1(NC(=O)C2SC(S2)=C(C(N)=O)C(O)=O)C2SCC(CSc3nnnn3C)=C(N2C1=O)C(O)=O
InchiKey: SRZNHPXWXCNNDU-PGEKIEPBSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
95453 BRD-A78723049 U2OS 0.12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
127035 BRD-A78723049 A375 0.04 uM 24 h 0.0 0.0 0.0 -0.26 -0.88 0.25
127055 BRD-A78723049 HA1E 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127121 BRD-A78723049 HELA 0.04 uM 24 h -0.24 -1.01 0.16 0.0 0.0 0.0
127155 BRD-A78723049 HT29 3.33 uM 24 h 0.0 0.0 0.0 0.25 0.9 0.21
127221 BRD-A78723049 MCF??7.00 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127257 BRD-A78723049 PC3 1.11 uM 24 h 0.0 0.0 0.0 0.27 0.97 0.34
127296 BRD-A78723049 THP1 0.04 uM 24 h 0.0 0.0 0.0 -0.37 -1.23 1.28
135063 BRD-A78723049 A549 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135119 BRD-A78723049 HEK293 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135189 BRD-A78723049 JURKAT 0.01 uM 24 h 0.0 0.0 0.0 0.29 1.02 0.47
135222 BRD-A78723049 MCF10A 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135289 BRD-A78723049 MDAMB231 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135336 BRD-A78723049 YAPC 0.01 uM 24 h -0.17 -0.73 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).