CMap Candidate Details
Structure:
| CMap ID: | C19244 |
| Pert ID: | BRD-K52827117 |
| Compound Name: | aprepitant |
| Targets: | TACR1 |
| MoA: | Tachykinin antagonist |
| SMILES: | C[C@@H](O[C@H]1OCCN(Cc2nc(=O)[nH][nH]2)[C@H]1c1ccc(F)cc1)c1cc(cc(c1)C(F)(F)F)C(F)(F)F |
| InchiKey: | NLYKDVVWGQZEED-OITMNORJSA-N |
| Compound Aliases: | -- |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 51617 | BRD-K52827117 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 51832 | BRD-K52827117 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 91450 | BRD-K52827117 | HUH7 | 6.66 uM | 72 h | 0.0 | 0.0 | 0.0 | 0.22 | 0.77 | 0.06 |