CMap Candidate Details

Structure:
CMap ID: C19249
Pert ID: BRD-K52836380
Compound Name: AZD-7545
Targets: --
MoA: --
SMILES: CN(C)C(=O)c1ccc(cc1)S(=O)(=O)c1ccc(NC(=O)[C@@](C)(O)C(F)(F)F)c(Cl)c1
InchiKey: DTDZLJHKVNTQGZ-GOSISDBHSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
8952 BRD-K52836380 A375 20 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
9440 BRD-K52836380 AGS 20 uM 6 h 0.0 0.0 0.0 -0.31 -1.04 0.67
9743 BRD-K52836380 H1299 20 uM 6 h -0.24 -1.02 0.18 0.37 1.32 1.59
10136 BRD-K52836380 HCC515 20 uM 24 h 0.0 0.0 0.0 0.26 0.91 0.23
10533 BRD-K52836380 HCT116 20 uM 6 h 0.0 0.0 0.0 -0.21 -0.72 0.04
10797 BRD-K52836380 HEPG2 20 uM 6 h -0.32 -1.35 0.98 0.0 0.0 0.0
11147 BRD-K52836380 MCF??7.00 20 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
11505 BRD-K52836380 NCIH2073 20 uM 6 h -0.24 -1.0 0.15 0.32 1.13 0.84
12066 BRD-K52836380 NCIH596 20 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12454 BRD-K52836380 PC3 20 uM 24 h -0.27 -1.11 0.36 0.0 0.0 0.0
12806 BRD-K52836380 SW480 20 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12960 BRD-K52836380 THP1 20 uM 6 h 0.23 0.94 0.06 -0.27 -0.91 0.31
13290 BRD-K52836380 U937 20 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13633 BRD-K52836380 VCAP 20 uM 6 h 0.21 0.87 0.01 0.2 0.72 0.02
115674 BRD-K52836380 A549 12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
115713 BRD-K52836380 HA1E 12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
115843 BRD-K52836380 HT29 12 uM 24 h -0.33 -1.38 1.08 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).