CMap Candidate Details

Structure:
CMap ID: C01927
Pert ID: BRD-A78942461
Compound Name: ICI-118551
Targets: ADRB2
MoA: Adrenergic receptor antagonist
SMILES: CC(C)NC(C)C(O)COc1ccc(C)c2CCCc21
InchiKey: VFIDUCMKNJIJTO-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6695 BRD-A78942461 A375 10 uM 24 h 0.0 0.0 0.0 0.34 1.22 1.15
7117 BRD-A78942461 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7415 BRD-A78942461 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7595 BRD-A78942461 HCC515 10 uM 6 h 0.22 0.93 0.05 -0.2 -0.68 0.02
7971 BRD-A78942461 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8204 BRD-A78942461 MCF??7.00 10 uM 6 h 0.21 0.86 0.01 0.26 0.92 0.25
8477 BRD-A78942461 PC3 10 uM 6 h -0.2 -0.85 0.01 0.33 1.16 0.9
8624 BRD-A78942461 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
100333 BRD-A78942461 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).