CMap Candidate Details

Structure:
CMap ID: C19281
Pert ID: BRD-K52930707
Compound Name: rescinnamine
Targets: ACE
MoA: Angiotensin converting enzyme inhibitor
SMILES: CO[C@H]1[C@@H](C[C@@H]2CN3CCc4c([nH]c5cc(OC)ccc45)[C@H]3C[C@@H]2[C@@H]1C(=O)OC)OC(=O)/C=C/c6cc(OC)c(OC)c(OC)c6
InchiKey: SZLZWPPUNLXJEA-QEGASFHISA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2899 BRD-K52930707 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3379 BRD-K52930707 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3523 BRD-K52930707 PC3 10 uM 24 h 0.3 1.24 0.53 -0.29 -0.99 0.5
3829 BRD-K52930707 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41788 BRD-K52930707 A375 10 uM 6 h -0.22 -0.91 0.05 0.0 0.0 0.0
42104 BRD-K52930707 A549 10 uM 6 h 0.0 0.0 0.0 0.31 1.1 0.69
42389 BRD-K52930707 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42709 BRD-K52930707 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.37 1.32 1.62
43012 BRD-K52930707 HT29 10 uM 6 h -0.34 -1.41 1.42 0.29 1.02 0.49
43202 BRD-K52930707 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.25 0.88 0.18
43576 BRD-K52930707 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43877 BRD-K52930707 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44134 BRD-K52930707 SKB 10 uM 24 h 0.0 0.0 0.0 -0.24 -0.81 0.13
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).