CMap Candidate Details

Structure:
CMap ID: C19289
Pert ID: BRD-K52959329
Compound Name: mitiglinide
Targets: ABCC8
MoA: Insulin secretagogue
SMILES: OC(=O)[C@H](CC(=O)N1C[C@H]2CCCC[C@H]2C1)Cc1ccccc1
InchiKey: WPGGHFDDFPHPOB-BBWFWOEESA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
121602 BRD-K52959329 HA1E 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121683 BRD-K52959329 MCF??7.00 1.11 uM 24 h -0.24 -0.98 0.12 0.36 1.28 1.34
129582 BRD-K52959329 A375 2.22 uM 24 h 0.28 1.17 0.36 0.0 0.0 0.0
129604 BRD-K52959329 HELA 0.03 uM 24 h 0.0 0.0 0.0 -0.26 -0.89 0.26
129635 BRD-K52959329 HT29 0.03 uM 24 h 0.22 0.9 0.02 0.25 0.87 0.17
129693 BRD-K52959329 PC3 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129727 BRD-K52959329 YAPC 0.25 uM 24 h 0.23 0.97 0.08 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).