CMap Candidate Details

Structure:
CMap ID: C19299
Pert ID: BRD-K52989797
Compound Name: clomipramine
Targets: SLC6A4; SLC6A2
MoA: SERT inhibitor
SMILES: CN(C)CCCN1c2ccccc2CCc2ccc(Cl)cc12
InchiKey: GDLIGKIOYRNHDA-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
3228 BRD-K52989797 HCC515 10 uM 24 h 0.0 0.0 0.0 0.35 1.23 1.19
3830 BRD-K52989797 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44987 BRD-K52989797 ASC 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.04 0.68
45280 BRD-K52989797 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.32 1.14 0.87
46103 BRD-K52989797 NPC 10 uM 24 h 0.0 0.0 0.0 -0.27 -0.92 0.33
46417 BRD-K52989797 PHH 10 uM 24 h 0.24 1.02 0.13 -0.2 -0.66 0.01
46742 BRD-K52989797 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
50019 BRD-K52989797 A549 10 uM 6 h 0.0 0.0 0.0 -0.32 -1.08 0.81
96483 BRD-K52989797 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121603 BRD-K52989797 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129605 BRD-K52989797 HELA 0.25 uM 24 h 0.17 0.69 0.0 -0.23 -0.76 0.07
129636 BRD-K52989797 HT29 0.01 uM 24 h 0.0 0.0 0.0 -0.25 -0.83 0.16
129661 BRD-K52989797 MCF??7.00 0.03 uM 24 h -0.27 -1.13 0.41 0.0 0.0 0.0
129694 BRD-K52989797 PC3 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129728 BRD-K52989797 YAPC 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).