CMap Candidate Details

Structure:
CMap ID: C19309
Pert ID: BRD-K53061490
Compound Name: ozagrel
Targets: TBXAS1
MoA: Thromboxane synthase inhibitor
SMILES: OC(=O)C=Cc1ccc(Cn2ccnc2)cc1
InchiKey: SHZKQBHERIJWAO-AATRIKPKSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
7683 BRD-K53061490 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.23 -0.76 0.07
24681 BRD-K53061490 A549 10 uM 6 h 0.0 0.0 0.0 -0.3 -1.01 0.57
25387 BRD-K53061490 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
91170 BRD-K53061490 HUH7 15 uM 72 h 0.19 0.8 0.0 0.16 0.58 0.0
99642 BRD-K53061490 U2OS 8 uM 6 h 0.0 0.0 0.0 -0.31 -1.05 0.72
124348 BRD-K53061490 HELA 3.33 uM 24 h -0.27 -1.13 0.4 0.0 0.0 0.0
124413 BRD-K53061490 JURKAT 10 uM 24 h 0.22 0.91 0.03 -0.23 -0.76 0.07
124464 BRD-K53061490 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124544 BRD-K53061490 YAPC 1.11 uM 24 h -0.19 -0.79 0.0 0.17 0.61 0.0
132327 BRD-K53061490 A375 0.01 uM 24 h 0.27 1.12 0.27 0.27 0.96 0.33
132386 BRD-K53061490 HA1E 2.22 uM 24 h 0.0 0.0 0.0 0.25 0.87 0.17
132420 BRD-K53061490 HEK293 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132461 BRD-K53061490 HT29 2.22 uM 24 h 0.24 1.02 0.13 0.33 1.16 0.91
132490 BRD-K53061490 MCF10A 2.22 uM 24 h -0.27 -1.14 0.42 0.0 0.0 0.0
132550 BRD-K53061490 MDAMB231 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132570 BRD-K53061490 PC3 0.25 uM 24 h 0.0 0.0 0.0 0.24 0.84 0.12
132600 BRD-K53061490 THP1 2.22 uM 24 h 0.0 0.0 0.0 0.21 0.75 0.04
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).