CMap Candidate Details

Structure:
CMap ID: C19318
Pert ID: BRD-K53097745
Compound Name: pterostilbene
Targets: PTGS2
MoA: PPAR receptor agonist; Cyclooxygenase inhibitor
SMILES: COc1cc(OC)cc(C=Cc2ccc(O)cc2)c1
InchiKey: VLEUZFDZJKSGMX-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
120853 BRD-K53097745 A375 10 uM 24 h 0.0 0.0 0.0 0.39 1.38 2.17
120882 BRD-K53097745 A549 0.125 uM 24 h 0.0 0.0 0.0 -0.23 -0.78 0.09
120898 BRD-K53097745 HA1E 3.33 uM 24 h 0.0 0.0 0.0 0.27 0.94 0.29
120929 BRD-K53097745 HEK293 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120993 BRD-K53097745 HELA 10 uM 3 h 0.0 0.0 0.0 0.25 0.9 0.22
121027 BRD-K53097745 MCF??7.00 10 uM 24 h 0.28 1.15 0.34 0.0 0.0 0.0
121065 BRD-K53097745 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121087 BRD-K53097745 YAPC 10 uM 24 h 0.0 0.0 0.0 -0.22 -0.75 0.07
129178 BRD-K53097745 HT29 0.08 uM 24 h 0.25 1.04 0.15 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).