CMap Candidate Details

Structure:
CMap ID: C01936
Pert ID: BRD-A79226577
Compound Name: tropisetron
Targets: HTR3A
MoA: Serotonin receptor antagonist
SMILES: CN1[C@H]2CC[C@@H]1CC(C2)OC(=O)C1C=Nc2ccccc12
InchiKey: RIJFNUHYNBVLOZ-DOOHLRMFSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6696 BRD-A79226577 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
7118 BRD-A79226577 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7268 BRD-A79226577 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.11 0.9
7596 BRD-A79226577 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7972 BRD-A79226577 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8478 BRD-A79226577 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8782 BRD-A79226577 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
51575 BRD-A79226577 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
100334 BRD-A79226577 U2OS 6.66 uM 6 h 0.0 0.0 0.0 0.36 1.28 1.42
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).