CMap Candidate Details

Structure:
CMap ID: C19386
Pert ID: BRD-K53318339
Compound Name: vinpocetine
Targets: PDE1A
MoA: Sodium channel blocker; Phosphodiesterase inhibitor
SMILES: CCOC(=O)C1=C[C@]2(CC)CCCN3CCc4c([C@H]23)n1c1ccccc41
InchiKey: DDNCQMVWWZOMLN-IRLDBZIGSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1756 BRD-K53318339 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
2106 BRD-K53318339 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
2484 BRD-K53318339 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42390 BRD-K53318339 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42710 BRD-K53318339 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43577 BRD-K53318339 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43878 BRD-K53318339 PHH 10 uM 24 h 0.0 0.0 0.0 -0.39 -1.32 1.71
44135 BRD-K53318339 SKB 10 uM 24 h 0.21 0.87 0.01 0.0 0.0 0.0
91385 BRD-K53318339 HUH7 10 uM 72 h 0.0 0.0 0.0 0.39 1.37 2.02
124316 BRD-K53318339 HEK293 0.37 uM 24 h 0.0 0.0 0.0 0.29 1.04 0.54
124349 BRD-K53318339 HELA 10 uM 24 h 0.0 0.0 0.0 0.25 0.88 0.18
124414 BRD-K53318339 JURKAT 3.33 uM 24 h 0.0 0.0 0.0 -0.32 -1.09 0.84
124485 BRD-K53318339 MDAMB231 0.04 uM 24 h 0.27 1.14 0.32 0.0 0.0 0.0
124515 BRD-K53318339 PC3 10 uM 24 h 0.25 1.06 0.18 -0.35 -1.19 1.15
132328 BRD-K53318339 A375 0.08 uM 24 h -0.27 -1.13 0.4 -0.21 -0.71 0.04
132355 BRD-K53318339 A549 0.08 uM 24 h -0.22 -0.9 0.04 0.4 1.42 2.2
132462 BRD-K53318339 HT29 0.01 uM 24 h 0.35 1.44 1.12 -0.26 -0.88 0.24
132491 BRD-K53318339 MCF10A 0.25 uM 24 h 0.24 1.01 0.12 0.0 0.0 0.0
132520 BRD-K53318339 MCF??7.00 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132601 BRD-K53318339 THP1 0.08 uM 24 h 0.0 0.0 0.0 -0.3 -1.02 0.61
132640 BRD-K53318339 YAPC 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).