CMap Candidate Details

Structure:
CMap ID: C19420
Pert ID: BRD-K53417444
Compound Name: OTS-167
Targets: --
MoA: --
SMILES: CN(C)C[C@H]1CC[C@@H](CC1)Nc1c(cnc2ccc(nc12)-c1cc(Cl)c(O)c(Cl)c1)C(C)=O
InchiKey: DKZYXHCYPUVGAF-JCNLHEQBSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
92964 BRD-K53417444 ASC 10 uM 24 h 0.0 0.0 0.0 0.22 0.78 0.06
93020 BRD-K53417444 CD34 0.37 uM 24 h 0.31 1.29 0.64 0.0 0.0 0.0
93189 BRD-K53417444 HEPG2 3.33 uM 24 h 0.0 0.0 0.0 -0.27 -0.92 0.31
93246 BRD-K53417444 HUVEC 0.12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93405 BRD-K53417444 NPC 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93519 BRD-K53417444 SKL 0.04 uM 24 h 0.31 1.29 0.64 0.0 0.0 0.0
124291 BRD-K53417444 A549 0.04 uM 24 h 0.31 1.3 0.68 0.0 0.0 0.0
124437 BRD-K53417444 JURKAT 0.125 uM 24 h 0.28 1.16 0.34 -0.26 -0.89 0.26
124529 BRD-K53417444 PC3 0.04 uM 24 h 0.0 0.0 0.0 0.26 0.94 0.28
132341 BRD-K53417444 A375 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132400 BRD-K53417444 HA1E 0.01 uM 24 h 0.2 0.85 0.01 0.0 0.0 0.0
132434 BRD-K53417444 HEK293 0.08 uM 24 h 0.0 0.0 0.0 -0.35 -1.18 1.14
132451 BRD-K53417444 HELA 0.01 uM 24 h 0.22 0.91 0.03 -0.34 -1.14 1.04
132472 BRD-K53417444 HT29 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132508 BRD-K53417444 MCF10A 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132536 BRD-K53417444 MCF??7.00 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132564 BRD-K53417444 MDAMB231 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132626 BRD-K53417444 THP1 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132650 BRD-K53417444 YAPC 0.01 uM 24 h 0.0 0.0 0.0 0.35 1.23 1.24
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).