CMap Candidate Details

Structure:
CMap ID: C19447
Pert ID: BRD-K53517854
Compound Name: fluvoxamine
Targets: SLC6A4
MoA: Selective serotonin reuptake inhibitor
SMILES: COCCCCC(c1ccc(cc1)C(F)(F)F)=N/OCCN
InchiKey: CJOFXWAVKWHTFT-XSFVSMFZSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
95320 BRD-K53517854 A549 10 uM 48 h 0.0 0.0 0.0 -0.27 -0.91 0.31
95403 BRD-K53517854 U2OS 10 uM 24 h 0.0 0.0 0.0 0.35 1.23 1.19
124299 BRD-K53517854 HA1E 10 uM 24 h -0.32 -1.34 0.98 0.0 0.0 0.0
124352 BRD-K53517854 HELA 1.11 uM 24 h 0.25 1.05 0.18 0.31 1.09 0.68
124384 BRD-K53517854 HT29 3.33 uM 24 h 0.19 0.79 0.0 0.0 0.0 0.0
124417 BRD-K53517854 JURKAT 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124449 BRD-K53517854 MCF10A 0.37 uM 24 h 0.0 0.0 0.0 0.28 0.98 0.37
124487 BRD-K53517854 MDAMB231 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124518 BRD-K53517854 PC3 0.125 uM 24 h 0.27 1.12 0.26 0.0 0.0 0.0
132331 BRD-K53517854 A375 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132423 BRD-K53517854 HEK293 0.03 uM 24 h 0.0 0.0 0.0 -0.27 -0.91 0.3
132522 BRD-K53517854 MCF??7.00 0.25 uM 24 h 0.0 0.0 0.0 0.24 0.86 0.16
132605 BRD-K53517854 THP1 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132642 BRD-K53517854 YAPC 0.74 uM 24 h 0.0 0.0 0.0 -0.32 -1.08 0.81
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).