CMap Candidate Details

Structure:
CMap ID: C19454
Pert ID: BRD-K53545112
Compound Name: CNQX
Targets: GRIA1
MoA: Glutamate receptor antagonist
SMILES: Oc1nc2cc(C#N)c(cc2nc1O)[N+](=O)[O-]
InchiKey: RPXVIAFEQBNEAX-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6780 BRD-K53545112 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
7011 BRD-K53545112 A549 10 uM 24 h 0.0 0.0 0.0 0.25 0.87 0.18
7342 BRD-K53545112 HA1E 10 uM 24 h 0.23 0.97 0.08 0.27 0.94 0.29
7685 BRD-K53545112 HCC515 10 uM 6 h 0.0 0.0 0.0 0.26 0.9 0.22
8013 BRD-K53545112 HT29 10 uM 6 h 0.0 0.0 0.0 0.29 1.03 0.51
8210 BRD-K53545112 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8390 BRD-K53545112 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
8703 BRD-K53545112 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99646 BRD-K53545112 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).