CMap Candidate Details

Structure:
CMap ID: C19477
Pert ID: BRD-K53610452
Compound Name: BRD-K53610452
Targets: --
MoA: --
SMILES: C[C@@H](CO)N1C[C@H](C)[C@H](CN(C)Cc2ccc(cc2)C(=O)Nc3ccccc3N)Oc4ccc(NC(=O)Nc5ccc(cc5)C(F)(F)F)cc4CC1=O
InchiKey: YPKBHAMQCQAOQB-FZLAZKPRSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
47003 BRD-K53610452 A375 10 uM 6 h -0.18 -0.76 0.0 0.36 1.26 1.29
47296 BRD-K53610452 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
47665 BRD-K53610452 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
47989 BRD-K53610452 HCC515 10 uM 6 h 0.0 0.0 0.0 0.21 0.76 0.05
48310 BRD-K53610452 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.29 1.03 0.51
48644 BRD-K53610452 HT29 10 uM 6 h -0.24 -1.0 0.14 0.0 0.0 0.0
48862 BRD-K53610452 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
49175 BRD-K53610452 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
49523 BRD-K53610452 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.37 -1.24 1.31
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).