CMap Candidate Details

Structure:
CMap ID: C01948
Pert ID: BRD-A79803969
Compound Name: memantine
Targets: GRIN1
MoA: Glutamate receptor antagonist
SMILES: CC12CC3CC(C)(C1)CC(N)(C3)C2
InchiKey: BUGYDGFZZOZRHP-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
49780 BRD-A79803969 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
49960 BRD-A79803969 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50123 BRD-A79803969 HA1E 10 uM 6 h 0.0 0.0 0.0 -0.25 -0.85 0.19
50313 BRD-A79803969 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.41 -1.37 2.02
50474 BRD-A79803969 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
51110 BRD-A79803969 VCAP 10 uM 6 h 0.26 1.09 0.22 0.22 0.78 0.07
52107 BRD-A79803969 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
52253 BRD-A79803969 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).